【职称】主任技师

【学位/学历】博士/研究生
   营养与食品卫生学
【学习经历】
1998.9-2003.6 华中科技大学同济医学院 本科
2003.9-2006.6 华中科技大学同济医学院 硕士
2013.9-2016.6 南方医科大学 博士
【工作经历】
   2006.07--2020.10  广东省疾病预防控制中心病原微生物检验所
   2020.10--2023.03  广东省疾病预防控制中心病原微生物检验所 副所长
   2023.03--         广东省疾病预防控制中心病原微生物检验所 所长
【研究方向及兴趣】
  新发突发传染病病原学快速精准鉴定、病原体分子流行病学研究和分子溯源研究
【论文代表作（近五年）】
(1)Molecular epidemiology and population immunity of SARS-CoV-2 in Guangdong (2022-2023) following a pivotal shift in the pandemic. Nat Commun. 2024 Aug 15;15(1):7033.
(2)Phylogeny and molecular evolution of the first local monkeypox virus cluster in Guangdong Province, China. Nat Commun 14, 8241 (2023).
(3)Immune evasion after SARS-CoV-2 Omicron BA.5 and XBB.1.9 endemic observed from Guangdong Province, China from 2022 to 2023  Virol J, 2024-11-20.
(4)A Food Poisoning Caused by Salmonella Enterica ( S. Enteritidis ) ST11 Carrying Multi-Antimicrobial Resistance Genes in 2019, China  Infect Drug Resist,2024-05-06.
(5)High prevalence and diversity of pre-CTXΦ alleles in the environmental Vibrio cholerae O1 and O139 strains in the Zhujiang River estuary  Environ Microbiol Rep,2024-05-06.
(6)Development of a quadruple qRT-PCR assay for simultaneous identification of hypervirulent and carbapenem-resistant Klebsiella pneumoniae   Microbiol Spectr, 2023-12-07.
(7)5.2017—2020年广东省副溶血弧菌引起的食源性暴发事件流行病学及病原特征分析,2023-09-05.
(8)Broadly neutralizing antibodies recognizing different antigenic epitopes act synergistically against the influenza B virus  J Med Virol,2022-09-06.
(9)An outbreak of Salmonella Hvittingfoss infection in a tourist group back from Hong Kong, Southeast China  J Infect,2022-02-15.
(10)Development and multi-center clinical trials of an up-converting phosphor technology-based point-of-care (UPT-POCT) assay for rapid COVID-19 diagnosis and prediction of protective effects  BMC Microbiol, 2022-02-03.
(11)Viral infection and transmission in a large, well-traced outbreak caused by the SARS-CoV-2 Delta variant  Nat Commun,2022-01-24.
(12)Sewage as a Possible Transmission Vehicle During a Coronavirus Disease 2019 Outbreak in a Densely Populated Community: Guangzhou, China, April 2020  Clin Infect Dis,2021-10-05.
(13)Seropositive Reaction Rates of 9 B-Cell Epitopes of the SARS-CoV-2 Spike Protein and the Relationship between the Epitopes and Neutralizing Antibody  Intervirology,2021-07-07.
(14)A newly identified linear epitope on non-RBD region of SARS-CoV-2 spike protein improves the serological detection rate of COVID-19 patients  BMC Microbiol, 2021-06-26.
(15)Genomic Evolution and Variation of SARS-CoV-2 in the Early Phase of COVID-19 Pandemic in Guangdong Province, China  Curr Med Sci,2021-04-20.
(16)A Case of New Variant COVID-19 First Emerging in South Africa Detected in Airplane Pilot - Guangdong Province, China, January 6, 2021  China CDC Wkly,2021-01-08.
(17)广东省肺炎克雷伯菌临床分离株病原特征分析,中国抗生素杂志,2020-01-01.：
【研究项目】（宋体小四加粗）
  建立自主可控的智慧化本地病原数据库和精准、快速的病原鉴定、分子溯源及特征分析平台（省级，500万）；超快核酸检测一体机研究项目（国家级，100万）；广东省新发传染病应急检测技术研究与应用（省科技厅，300万）；国家疾控局公共卫生人才培养项目（国家级，180万）
【获奖情况】
  广东省卫生应急技能标兵、全国卫生应急技能标兵、广东省抗击新冠肺炎先进个人、国家公共卫生领军人才等