【职　　称】 教授（博士生导师） 

【所属部门】 劳动卫生与环境卫生学系

【电子邮件】[email protected]

【研究方向】环境流行病学、环境毒理学

【研究生招生专业】劳动卫生与环境卫生学、公共卫生硕士（MPH）

 

【学术简历】

        91吃瓜 ，教授/博士生导师，劳动卫生与环境卫生学系主任，教育部“环境与健康国际合作联合实验室”副主任。入选国家高层次人才特殊支持计划青年拔尖人才，广东省杰出青年科学基金获得者。主要研究方向为环境污染物的生物监测及健康风险研究，重点关注大气超细颗粒物和新污染物暴露的健康效应及分子机制。目前已主持国家重点研发计划国际合作项目和国家自然科学基金等十余项省部级以上项目。目前以第一作者/通讯（含并列）作者发表SCI论文50余篇；参编5本专著/教材；目前担任广东省环境诱变剂学会秘书长。。

 

【教育经历】

2003/09-2009/12，91吃瓜 ，环境科学与工程学院，环境科学，博士（导师：仇荣亮教授）

2007/04-2008/08，美国佛罗里达大学，食品与农业学院，国家留学基金委博士生联合培养（导师：Lena Ma教授）

1999/09-2003/06，河南大学，环境与规划学院 ，资源环境与城乡规划管理，本科

 

【研究工作经历】

2021/02       至今，91吃瓜 ，91吃瓜 ，教授/博导

2018/12-2019/12，澳大利亚墨尔本大学，访问学者

2015/01-2021/01，91吃瓜 ，91吃瓜 ，副教授/博导

2012/07-2015/01，91吃瓜 ，91吃瓜 ，讲师/硕导

2010/07-2012/06，91吃瓜 ，91吃瓜 ，师资博士后（导师：陈雯教授）

2010/01-2010/06，91吃瓜 ，广东省环境污染控制与修复技术重点实验室，科研助理

 

【主要社会兼职】

  1. 广东省环境诱变剂学会，秘书长
  2. 中国环境科学学会环境医学与健康分会，委员
  3. 中国环境诱变剂学会环境表观遗传专委会，委员                  
  4. 中国环境诱变剂学会环境流行病学专委会，委员
  5. 广东省毒理学会，常务理事

 

【主要承担的课题】

1.国家重点研发计划项目课题：PFAS和抗生素类新污染物人体健康危害与生态毒性表征（主持，2024.12-2027.11）

2.国家重点研发计划国际创新合作重点专项：交通源超细颗粒物暴露与神经退行性疾病风险评估的关键技术及应用（主持，2019.08-2022.12）

3.国家自然科学基金面上项目：新兴全氟化合物替代品早期暴露对子代神经发育的影响及脂质代谢的作用机制（主持，2021.01-2024.12）

4.国家自然科学基金面上项目：生命早期全氟化学物暴露影响儿童疫苗接种免疫应答的机制（主持，2017.01-2020.12）

5.国家自然科学基金青年项目：锌镉处理下超富集植物的差异蛋白质表达及金属耐性机理研究（主持，2011.01-2013.12）

6.广东省自然科学基金杰出青年项目：大气超细颗粒物的神经毒性及脂质代谢介导的作用机制（主持，2021.01-2024.12）

7.广东省自然科学基金面上项目：基于暴露组学的环境污染物致新生儿不良出生结局的队列研究（主持，2016.06-2019.06）

8.有机地球化学国家重点实验室开放基金：全氟化学物暴露与新生儿不良出生结局及全基因组DNA甲基化的相关性研究（主持，2017.01-2018.12）

9.广州市科技计划科技菁英“领航”项目：新兴全氟化合物替代品的子代神经毒性及暴露风险评估（主持，2024.01-2026.12）

10.中央高校青年教师重点培育项目：胎儿宫内生长受限与儿童早期神经认知功能的相关性——基于生命早期环境污染物暴露与不良出生结局的队列研究（主持，2017.01-2018.12）

11.中国博士后基金第四批特别资助项目：microRNA调控苯代谢关键酶表达及其效应研究（主持，2011-2013）

12.中国博士后科学基金第48批资助项目：电子废弃物处置区域的环境特征污染物与人体健康损伤（主持，2010-2012）

 

【近五年主要论著】（#并列第一作者，*通讯作者）

 

  1. Cai D#, Li SP#, Guo YT, Chou WC, Mohammed Z, Qiu RL, Hu G, Qi J, Ren M, Xiang M, Li Z, Zhou Y, Huang J, Kong M, Xie Y, Tang C, Lin LZ, Yu Y*, Dong GH*, Zeng XW*. Effects of serum insulin and insulin-like growth factor 1 levels on the association between fetal growth and per- and polyfluoroalkyl substance exposure based on a nested case-control study. Environmental Science & Technology. 2025. doi.org/10.1021/acs.est.4c08752.
  2. Li SP, Zhao WH, Zhang J, Jiang WT, Zhu JY, Luo YX, Xiang P, Bloom M, Jalava P, Gong GH,  Zeng XW*. Effects of early-life F-53B exposure on thyroid function in juvenile rats: The role of the cAMP signaling pathway. Journal of Hazardous Materials. 2025. 489:137751.
  3. Zeng HX, Qin SJ, Wu QZ, Zeng QG, Li JH, Oudin A, Kannien KM, Yang M, Jalava P, Dong GH, Zeng XW*. Circular RNA circ_0061183 regulates microglial polarization induced by airborne ultrafine particles in HMC3 cells via sponging miR-98-5p. Journal of Hazardous Materials. 2025. 484:136724.
  4. Li JH#, Zeng HX#, Wei J, Wu QZ, Qin SJ, Zeng QG, Zhao B, Dong GH, Shen JC*, Zeng XW*. Long-term exposure to PM2.5 and its constituents and visual impairment in schoolchildren: A population-based survey in Guangdong province, China. Environment International. 2025.195: 109270.
  5. Qin SJ, Zeng QG, Zeng HX, Meng WJ, Wu QZ, Lv Y, Dai J, Dong GH, Zeng XW*. Novel perspective on particulate matter and Alzheimer's disease: Insights from adverse outcome pathway framework. Environmental Pollution. 2025. 367:125601.
  6. Zeng HX, Qin SJ, Andersson J, Li SP, Zeng QG, Li JH, Wu QZ, Oudin A, Kannien KM, Jalava P, Dong GH, Zeng XW*. The emerging role of particulate matter-changed non-coding RNAs in the pathogenesis of Alzheimer's disease: A comprehensive in silico analysis and review. Environmental Pollution. 2025. 366:125440.
  7. Zhang J, Li SP, Li QQ, Zhang YT, Dong GH, Canchola A, Zeng XW*, Chou WC*. Development of a physiologically based pharmacokinetic (PBPK) model for F-53B in pregnant mice and its extrapolation to humans. Environmental Science & Technology. 2024. 58:18928.
  8. Wu QZ, Zeng HX, Andersson J, Oudin A, Kanninen KM, Xu MW, Qin SJ, Zeng QG, Zhao B, Zheng M, Jin N, Chou WC, Jalava P, Dong GH, Zeng XW*. Long-term exposure to major constituents of fine particulate matter and neurodegenerative diseases: A population-based survey in the Pearl River Delta Region, China. Journal of Hazardous Materials. 2024. 470:134161.
  9. Qin SJ, Zeng QG, Zeng HX, Li SP,  Andersson J, Zhao B, Oudin A, Kannien KM, Jalava P, Jin NX, Yang M, Lin LZ, Liu RQ, Dong GH, Zeng XW*. Neurotoxicity of fine and ultrafine particulate matter: A comprehensive review using a toxicity pathway-oriented adverse outcome pathway framework. Science of the Total Environment. 2024.947:174450.
  10. Li SP, Zeng HX, Qin SJ, Li QQ, Wu LY, Wu QZ,. Lin LZ, Dong GH, Zeng XW*. Effects on synaptic plasticity markers in fetal mice and HT22 neurons upon F-53B exposure: the role of PKA cytoplasmic retention. Environmental & Health (Wash). 2024. 2:776.
  11. Li SP, Qin SJ, Zeng HX, Chou WC, Oudin A, Kannien KM, Jalava P, Dong, Zeng XW*. Adverse outcome pathway for the neurotoxicity of per- and polyfluoroalkyl substances: A systematic review. Eco-Environment & Health. 2024. 3:476.
  12. Guo YT#, Huang JB#, Xue JC, Qin SJ, Cai D, Wu QZ, Chu C, Tang C, Xie Y,Lin LZ, Dong GH, Zeng XW*. Intrauterine exposure to long-chain perfluorocarboxylic acids (PFCAs) were associated with reduced primary bile aci8des in three-year-old children: Finding from a prospective birth cohort study. Environmental Pollution. 2024. 360:124583.
  13. Li SP#, Wu LY#, Zeng HX, Zhang J, Qin SJ, Liang LX, Andersson J, Meng WJ, Chen XY, Wu QZ, Lin LZ, Chou WC, Dong GH. Zeng XW*. Hepatic injury and ileitis associated with gut microbiota dysbiosis in mice upon F-53B exposure. Environmental Research. 2024. 248:118305.
  14. Yang M, Wu QZ, Zhang YT, Leskinen A, Wang XF, Komppula M, Hakkarainen H, Roponen M, Jin NX, Tan WH, Xu SL, Lin LZ, Liu RQ, Zeng XW*, Dong GH*. Toxicological evaluation and concentration of airborne PM0.1 in high air pollution period in Guangzhou, China. Science of the Total Environment. 2024.921:171224. 
  15. Qin XD#, Zhou Y#, Bloom B#, Qian Z, Geiger SD, Vaughn MG, Chu C, Li QQ, Yang BY, Hu LW, Yu Y,  Zeng XW*, Dong GH*. Prenatal exposure to PFAS, associations with preterm birth and modification by maternal estrogen levels: The Maoming birth study. Environmental Health Perspectives. 2023.131:117006.

  16. Zeng XW#, Bloom M#, Wei F#, Liu L, Qin J, Xue L, Wang S, Huang G, Teng M, He B, Mao X, Chu C, Lin S*, Dong GH*, Tan W*. Perfluoroalkyl acids in follicular fluid and embryo quality during IVF: a prospective IVF cohort in China. Environmental Health Perspectives. 2023.131:27002.

  17. Zhang YT#, Bao H#, Zhang L#, Wen S, Tan W, Zeeshan M, Sun MK, Chu C, Gui ZH, Lin LZ, Liu RQ, Zeng XW*, Yu Y*, Dong GH*. Health risk assessment of perfluorooctane sulfonate and perfluorooctanoic acid exposure in China based on epidemiological data. Hygiene and Environmental Health Advances. 2023. 7: 100066.

  18. Li QQ#, Huang J#, Cai D#, Chou WC, Zeeshan M, Chu C, Zhou Y, Lin L, Ma H, Xie Y, Dong GH*, Zeng XW*. Prenatal exposure to legacy and alternative PFAS and neuropsychological development trajectories over the first three years of life. Environmental Science & Technology. 2023. 57: 3746.

  19. Yang M#, Wu QZ#, Zhang YT, Leskinen A, Komppula M, Hakkarainen H, Roponen M, Xu SL, Lin LZ, Liu RQ, Hu LW, Yang BY, Zeng XW*, Dong GH*, Jalava P. Concentration, chemical composition and toxicological responses of the ultrafine fraction of urban air particles in PM1. Environment International. 2022.170: 107661.

  20. Li QQ#, Liu JJ#, Su F, Zhang YT, Wu LY, Chu C, Zhou YZ, Shen X, Xiong S, Geiger SD,  Qian ZM, McMillin SE, Dong GH, Zeng XW*. Chlorinated polyfluorinated ether sulfonates and thyroid hormone levels in adults: Isomers of C8 Health Project in China. Environmental Science & Technology. 2022.56:6152.

  21. Liu JJ#, Cui XX#, Tan YW#, Dong PX, Ou YQ, Li QQ, Chu C, Wu LY, Liang LX, Qin SJ, Zeeshan M, Zhou Y, Hu LW, Liu RQ, Zeng XW*, Dong GH*, Zhao XM*. Per- and perfluoroalkyl substances alternatives, mixtures and liver function in adults: A community-based population study in China. Environment International. 2022.163:107179.

  22. Lin LZ#, Zeng XW#, Deb B, Tabet M, Xu SL, Wu QZ, Zhou Y, Ma HM, Chen DH, Chen GB, Yu HY, Yang BY, Hu Q, Yu YJ, Dong GH, Hu LW*. Outdoor light at night, overweight, and obesity in school-aged children and adolescents. Environmental Pollution. 2022.305:119306.

  23. Wu QZ, Xu SL, Tan YW, Qian Z, Vaughn MG, McMillin SE, Dong P, Qin SJ, Liang LX, Lin LZ, Liu RQ, Yang BY, Chen GB, Zhang WJ, Hu LW, Zeng XW*, Dong GH*. Exposure to ultrafine particles and childhood obesity: A cross-sectional analysis of the Seven Northeast Cities (SNEC) Study in China. Science of the Total Environment. 2022.846:157524.

  24. Su F, Zeeshan M, Xiong LH, Lv JY, Wu Y, Tang XJ, Zhou Y, Ou YQ, Huang WZ, Feng WR*, Zeng XW*, Dong GH*. Co-exposure to perfluoroalkyl acids and heavy metals mixtures associated with impaired kidney function in adults: A community-based population study in China. Science of the Total Environment. 2022.839:156299.

  25. Zeng XW, Lodge CJ, Lowe AJ, Guo Y, Abramson M, Bowatte G, Hu LW, Yang BY, Chen ZX*, Dharmage SC*, Dong GH*. Current pet ownership modifies the adverse association between long-term ambient air pollution exposure and childhood asthma. Clinical and Translational Allergy. 2021.11:e12005.

  26. Ye WL#, Chen ZX#, Xie YQ#, Kong ML#, Li QQ, Yu S, Chu C, Dong GH, Zeng XW*. Associations between serum isomers of perfluoroalkyl acids and metabolic syndrome in adults: Isomers of C8 Health Project in China. Environmental Research. 2021.196.110430.

  27. Ou Y#, Zeng XW#, Lin S*, Bloom MS, Han F, Xiao X, Wang H, Matala R, Li X, Qu Y, Nie Z, Dong GH*, Liu X*. Gestational exposure to perfluoroalkyl substances and congenital heart defects: A nested case-control pilot study. Environment International.  2021.154:106567.

  28. Zeng XW, Lowe AJ, Lodge CJ, Heinrich J, Roponen M, Jalava P, Guo Y, Hu LW, Yang BY, Dharmage SC, Dong GH*. Greenness surrounding schools is associated with lower risk of asthma in schoolchildren. Environment International. 2020. 143:105967.

  29. Zeng XW, Li QQ, Chu C, Ye WL, Yu S, Ma HM, Zeng XY, Zhou Y, Yu HY, Hu LW, Yang BY, Dong GH*. Alternatives of perfluoroalkyl acids and hepatitis B virus surface antibody in adults: Isomers of C8 Health Project in China. Environmental Pollution. 2020. 259: 113857.

  30. Cai D#, Li QQ#, Chu C, Wang SZ, Tang YT, Appleton AA, Qiu RL, Yang BY, Hu LW, Dong GH, Zeng XW*, High trans-placental transfer of perfluoroalkyl substances alternatives in the matched maternal-cord blood serum: Evidence from a birth cohort study. Science of the Total Environment. 2020. 705: 135885.

  31. Li J#, Cai D#, Chu C, Li QQ, Zhou Y, Hu LW, Yang BY, Dong GH, Zeng XW*, Chen D*. Transplacental transfer of per- and polyfluoroalkyl substances (PFASs): Differences between preterm and full-term deliveries and associations with placental transporter mRNA expression. Environmental Science & Technology. 2020.54:5062.

  32. Wu QZ#, Li S#, Yang BY#, Bloom M#, Shi Z, Knibbs L, Dharmage S, c, Jalaludin B, Jalava P, Ropenen M, Lin S, Chen G, Guo Y, Xu SL, Yu HY, Zeeshan M, Hu LW, Yu Y*, Zeng XW*, Dong GH*. Ambient airborne particulates of diameter ≤1 μm, a leading contributor to the association between ambient airborne particulates of diameter ≤2.5 μm and children’s blood pressure. Hypertension. 2020.75:347. 

 

【书稿专著】

  1. 第二主编, 《现代环境流行病学》，科学出版社，2023年.
  2. 第一主编，《环境卫生学思政案例集》，91吃瓜 出版社，2023年.
  3. 编委，《预防医学》课程思政案例库，人民卫生出版社，2024年.
  4. 第三副主编, 《空气颗粒物与健康》，“十三五”国家重点出版物，湖北科学技术出版社，2019年.
  5. 编委，《环境与健康》，科学出版社“十四五”普通高等教育研究生规划教材，2024年.
  6. 参编，《Ambient Air Pollution and Health Impact in China》, Springer Nature出版，2017年.

 

【学术科研奖励】

  1. 国家高层次人才特殊支持计划青年拔尖人才2021年

  2. 91吃瓜 “逸仙学者”优秀学者2021年

  3. 中华医学科技奖，三等奖（2/8）

  4. 2019年度华夏医学科技奖，三等奖（5/6）
  5. 2018年度广东省自然科学奖，二等奖（5/8）
  6. 2018年度广东省环境保护科学技术奖，一等奖（10/15）
  7. 2016年度“广东特支计划” 百千万工程青年拔尖人才
  8. 2011年度“91吃瓜 优秀博士后”

 

【博士后/专职研究人员招聘】

        常年招聘从事环境毒理学、环境化学、环境流行病学、环境科学或生物信息学等领域的博士后和专职科研人员，工资26-40万，有校内公寓，享有正式编制职工医疗、子女入学等福利待遇。优秀者在聘期结束或聘期内可直接申请学校的教授/副教授职位，欢迎各位有志于投身环境健康研究领域的青年才俊加入课题组！